Chemical analysis of functionalized polymer surfaces

Structure analysis and molecular recognition studies of bio-functionalized surfaces

Biological and chemical reactions involved in physiological processes are often complex and very sophisticated. Such processes can be mimicked in the laboratory to obtain important knowledge, valuable for the development of new diagnostic methods, drugs and biosensors. This thesis includes investigations of bio-functionalized surfaces that can be used as model systems to mimic naturally existin...

Phosphopeptide enrichment on functionalized polymer microspots for MALDI-MS analysis.

On-plate enrichment of phosphopeptide digests followed by MALDI-MS is attractive for analyzing small quantities of phosphoproteins because it involves minimal sample handling and reduces sample loss. This work describes a method for modification of Si wafers, which serve as MALDI plates, with 250 microm-diameter microspots of phosphopeptide-binding polymer brushes enclosed by a hydrophobic poly...

Quantitative CD ATR-FTIR and CD SEM-EDX analyses of locally amino-functionalized polymer surfaces

From superhydrophobicity and water repellency to superhydrophilicity: smart polymer-functionalized surfaces.

pH-responsive surfaces, reversibly switching between superhydrophilicity and superhydrophobicity/water repellency, are developed by "grafting from" a pH-sensitive polymer onto a hierarchically micro/nano-structured substrate. We quantify the water repellency by investigating the restitution coefficient of water droplets bouncing off the surfaces. The water repellent state requires appropriate h...

Interactions between surfactant-coated surfaces in hydrocarbon liquids containing functionalized polymer dispersant

Knowledge of the structure and interactions of mixed polymer/surfactant colloidal systems is essential for simultaneously controlling the stability and rheological properties of colloidal dispersions such as emulsions and lubricating oils [1, 2]. The surfactant and polymer together provide stability against coagulation and control the viscosity of the ̄uid, the practical aim being to produce hig...